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Sunday, December 07, 2008

FACTT trial Fluid Management in Patients With ALI

Fluid Management in Patients With ALI
Fluids and Catheters Treatment Trial (FACTT) compares the patients receiving PAC or a central venous catheter (CVC) with one of two fluid management strategies (conservative vs. liberal).
  1. randomized,
  2. multicenter trial is designed to include 1000 patients.
  3. The primary endpoint is mortality at 60 days. (no change)
  4. Secondary endpoints include ventilator free days and (with conservative fluid strategy decreased)
  5. organ failure free days.(no change)

adapting more conservative fluid management is better while treating ALI and ARDS patients.