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Tuesday, December 16, 2008

Renal replacement therapy for acute kidney injury ...[Crit Care Resusc. 2008] - PubMed Result

Renal replacement therapy for acute kidney injury ...[Crit Care Resusc. 2008] - PubMed Result: "BACKGROUND: There are few published data on the practice of renal replacement therapy (RRT) in Australian and New Zealand intensive care units. These data are essential for designing trials to compare new treatment approaches with 'standard care'. DESIGN: A prospective survey of RRT practice in ICUs interested in participating in the Australian and New Zealand Randomised Evaluation of Normal vs. Augmented Level (RENAL) Replacement Therapy in ICU Trial. SETTING AND PARTICIPANTS: 34 ICUs in Australia and New Zealand. OUTCOME MEASURES: Information on choice of therapeutic modality, technique, dose prescription, dose adjustment, technology, and replacement fluid composition before the initiation of the trial. RESULTS: All ICUs used continuous veno-venous RRT (CRRT) as the therapy of first choice. The most common technique, continuous veno-venous (CVV) haemodiafiltration, was used in 62% (21/34) of ICUs, followed by CVV haemofiltration in 35%, (12/34) and CVV haemodialysis in 3% (1/34). Replacement fluid was given prefilter (pre-dilution) in most cases (94%). Lactate-based replacement fluid or dialysate accounted for 55% of all commercial fluid supplied by pharmacies to participating ICUs, bicarbonate-based fluid for 43% and citrate-based fluid for 2%."

Source Pubmed