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"CONCLUSIONS: We conclude that patients with preexisting spinal canal pathology have a higher
incidence of neurologic complications after neuraxial blockade (1.1%; 95% CI 0.5%–2.0%) than that
previously reported for patients without such underlying pathology. However, in the absence of a
control group of surgical patients with similar anatomic pathology undergoing general anesthesia, we
cannot determine whether the higher incidence of neurologic injury is secondary to the surgical
procedure, the anesthetic technique, the natural history of spinal pathology, or a combination of
factors and the relative contributions of each. (Anesth Analg 2010;111:1511–9)"
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